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LNSMGQD

LNSMGQD is a peptide that targets the adhesive interfaces of desmoglein (DSG1 and DSG3) core glycoproteins, interfering with the single peptide (SP) components of DSG trans-interactions. By binding to DSGs, LNSMGQD prevents the loss of DSG trans-interactions induced by autoantibodies, inhibits the activation of p38 MAPK, and prevents keratin filament retraction. It is useful for research into autoimmune skin diseases such as pemphigus vulgaris.

Product Specifications

Field of Research

Signal Transduction

Molecular Weight

763.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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