β-catenin inhibitory peptoid
β-catenin inhibitory peptoid (compound 13) disrupts the interaction between β-catenin and TCF with an IC50 of 5.44 μM. It inhibits Wnt signaling in prostate cancer cell lines (IC50 = 0.105 μM) and androgen receptor (AR) signaling (IC50 = 1.02 μM) . This compound significantly reduces cell proliferation in prostate cancer cell lines.
Product Specifications
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Molecular Weight
1057.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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