Tat-braftide

Tat-braftide is a peptide inhibitor designed to block the dimerization of BRAF, thereby inhibiting its kinase activity. After disrupting BRAF dimers, Tat-braftide facilitates proteasomal degradation of BRAF proteins, directly reducing BRAF kinase activity and diminishing MAPK pathway activation. Tat-braftide is useful for studying RAF kinase function within the MAPK signaling pathway and researching BRAF-mutant cancers.