PROTAC SMARCA2 degrader-12
Product Specifications
UNSPSC Description
SMARCA2 degrader-13 (compound I-406) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC50 90 after 24 h of treatment[1].
Target Antigen
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-smarca2-degrader-12.html
Smiles
NC1=C(C=C(C2=C(C=CC=C2)O)N=N1)N3CC4N(C5=NC=C(C6=CC[C@@H](C(N[C@@H](C(C)(C)C)C(N7[C@@H](C[C@H](C7)O)C(NCC8=CC=C(C9=C(N=CS9)C)C=C8)=O)=O)=O)CC6)C=N5)C(CC4)C3
Molecular Weight
912.11
References & Citations
[1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163874/PROTAC-SMARCA2-degrader-12-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163874/
Clinical Information
No Development Reported
CAS Number
2568277-42-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6377009-01 0.1 mL
EFEMP2 (Protein UPH1, Fibulin-4, FIBL-4, EGF-containing Fibulin-like Extracellular Matrix Protein 2, FBLN4, UNQ200/PRO226) APC
Ask
View Details MBS6377009-02 5x 0.1 mL
EFEMP2 (Protein UPH1, Fibulin-4, FIBL-4, EGF-containing Fibulin-like Extracellular Matrix Protein 2, FBLN4, UNQ200/PRO226) APC
Ask
View Details 
MBS1203418 Inquire
Recombinant Crucihimalaya wallichii Protein ycf2 A (ycf2-A), partial
Ask
View Details 