AP1867-3-(aminoethoxy)
Product Specifications
UNSPSC Description
AP1867-3-(aminoethoxy), the AP1867 based moiety, is a synthetic ligand for FKBP. AP1867-3-(aminoethoxy) can be used in the synthesis of PROTAC FKBP12 F36V degrader[1].
Target Antigen
FKBP; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Apoptosis;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation;PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ap1867-3-methoxyethylamine.html
Purity
98.60
Solubility
DMSO : 240 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(C([C@H](C2=CC(OC)=C(OC)C(OC)=C2)CC)=O)CCCC1)O[C@@H](C3=CC=CC(OCCN)=C3)CCC4=CC=C(OC)C(OC)=C4
Molecular Weight
678.81
References & Citations
[1]Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129363/AP1867-3-aminoethoxy-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129363/AP1867-3-aminoethoxy-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2127390-15-0
Available Sizes
Curated Selection
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