CBP/p300-IN-10
CBP/p300-IN-10 is a highly potent histone acetyltransferase EP300 and CREBBP with IC50 values of 26 nM and 39 nM, respectively. CBP/p300-IN-10 can be used to research anticancer[1].
Product Specifications
CAS Number
[2259641-71-7]
UNSPSC
12352005
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbp-p300-in-10.html
Purity
98.69
Solubility
DMSO : 10.5 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C(N1[C@H](C[C@H](C1)F)C(NC2=CC=C(NN=C3)C3=N2)=O)C4(C5=CC=C(C=C5)OC(F)F)CCC(F)(CC4)F
Molecular Formula
C25H24F5N5O3
Molecular Weight
537.48
References & Citations
[1]Naito, Hiroyuki, et al. Preparation of amino acid amide derivatives such as L- and D-prolinamide derivatives as Ep300/CREBBP inhibitors. WO2018235966A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CBP/p300
Available Sizes
Curated Selection
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