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BA 1 (TFA)

BA 1 TFA is a potent agonist for the bombesin (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM[1].

Product Specifications

UNSPSC

12352209

Target

Bombesin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ba-1-tfa.html

Purity

99.35

Solubility

H2O : 16.67 mg/mL (ultrasonic)

Smiles

CCCC[C@@H](C(N)=O)NC([C@@H](NC([C@@H](NC(CCNC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](CC1=CC=C(O)C=C1)N)=O)CCC(N)=O)=O)CC2=CNC3=C2C=CC=C3)=O)C)=O)=O)=O)CC4=CN=CN4)=O)CC5=CC=CC=C5)=O.O=C(O)C(F)(F)F

Molecular Formula

C59H77F3N14O13

Molecular Weight

1247.32

References & Citations

[1]Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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