Insect repellent M 3535

Insect repellent M 3535 (Ethyl butylacetylaminopropionate; IR-3535) is a potent anthelmintic that is toxic to zebrafish with a lethal concentration 50 (LC50) of 140 mg/L at 72 hours post fertilization (hpf) . Insect repellent M 3535 causes morphological abnormalities and cardiac defects in early embryonic development of zebrafish by potentially inducing the production and accumulation of reactive oxygen species (Reactive Oxygen Species) and activating oxidative stress responses, thereby activating the endogenous apoptosis pathway[1].

Product Specifications

CAS Number

[52304-36-6]

Product Name Alternative

Ethyl butylacetylaminopropionate; IR-3535

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/insect-repellent-m-3535.html

Purity

99.92

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CCCCN(CCC(=O)OCC)C(=O)C

Molecular Formula

C11H21NO3

Molecular Weight

215.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Qiang Luo, et al. Developmental and cardiac toxicity assessment of Ethyl 3- (N-butylacetamido) propanoate (EBAAP) in zebrafish embryos. Aquat Toxicol. 2023 Aug:261:106572.