Human uPAR / PLAUR (115-305) Protein, His Tag (MALS verified)
Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA
Product Specifications
Expression Region
Leu 115 - Gly 305
Reactivity
Human
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Immunology & Inflammation
Endotoxin
1.0 EU per μg
Purity
90%
Form
Powder
Molecular Weight
23 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23 kDa. The protein migrates as 30-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
Q03405
Preservative
PBS, pH 7.4
Available Sizes
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