Human IRAK4 Protein, GST Tag (active enzyme, HPLC verified)
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Specifications
Expression Region
Asn 2 - Ser 460
Reactivity
Human
Conjugation
Unconjugated
Tag
N-GST
Field of Research
Immunology & Inflammation
Endotoxin
1.0 EU per μg
Purity
90%
Form
Liquid
Molecular Weight
76.9 kDa
Storage Conditions
-70°C
Notes
For research use only.
Applications Notes
This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 76.9 kDa. The protein migrates as 70-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
Q9NWZ3
Preservative
50 mM HEPES, 300 mM NaCl, pH 7.5
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
