Psalmotoxin 1 TFA

Psalmotoxin 1 (PcTx1) TFA is a protein toxin that binds to the subunit interfaces of acid-sensing ion channel 1a (ASIC1a) . It selectively and effectively inhibits ASIC1a by enhancing its apparent affinity for H+ (IC50: 0.9 nM) . Psalmotoxin 1 TFA induces apoptosis and inhibits cancer cell migration, proliferation, and invasion. This compound is applicable in cancer or neurological disease research.