NCGC00351170
Product Specifications
UNSPSC Description
NCGC00351170 is an antiplatelet agent that disrupts the calcium and integrin-binding protein 1 (CIB1)-αIIbβ3 interaction. NCGC00351170 inhibits thrombin-induced human platelet aggregation[1].
Target Antigen
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ncgc00351170.html
Solubility
DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1=[N+]([O-])ON=C1C(C2=CC=CC=C2OC)=O)C3=C(OC)C=CC=C3
Molecular Weight
354.31
References & Citations
[1]Golla K, et al. Small-Molecule Disruptors of the Interaction between Calcium-and Integrin-Binding Protein 1 and Integrin αIIbβ3 as Novel Antiplatelet Agents[J]. ACS Pharmacology & Translational Science, 2024.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162558/NCGC00351170-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162558/NCGC00351170-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
886536-76-1
Available Sizes
Curated Selection
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