NCGC00351170
NCGC00351170 is an antiplatelet agent that disrupts the calcium and integrin-binding protein 1 (CIB1) -αIIbβ3 interaction. NCGC00351170 inhibits thrombin-induced human platelet aggregation[1].
Product Specifications
CAS Number
[886536-76-1]
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ncgc00351170.html
Purity
99.05
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=[N+]([O-])ON=C1C(C2=CC=CC=C2OC)=O)C3=C(OC)C=CC=C3
Molecular Formula
C18H14N2O6
Molecular Weight
354.31
References & Citations
[1]Golla K, et al. Small-Molecule Disruptors of the Interaction between Calcium-and Integrin-Binding Protein 1 and Integrin αIIbβ3 as Novel Antiplatelet Agents[J]. ACS Pharmacology & Translational Science, 2024.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
249518 50 µg
NTRK2 (Neurotrophic Tyrosine Kinase, Receptor, Type 2, GP145-TrkB, TRKB)
Sign In for Pricing
View Details 
D8065-31F-ML750 100 µL
DPP8, CT (Dipeptidyl Peptidase 8, DP8, Dipeptidyl Peptidase VIII, DPP VIII, Prolyl Dipeptidase DPP8, Dipeptidyl Peptidase IV-related Protein 1, DPRP-1, MSTP141, DPRP1, MSTP097, MSTP135) (MaxLight 750) discontinued
Sign In for Pricing
View Details IC605U-100UG 100 µg
Human IL-5 Alexa Fluor 350 Antibody (Clone 9906)
Sign In for Pricing
View Details