NCGC00351170
NCGC00351170 is an antiplatelet agent that disrupts the calcium and integrin-binding protein 1 (CIB1) -αIIbβ3 interaction. NCGC00351170 inhibits thrombin-induced human platelet aggregation[1].
Product Specifications
CAS Number
[886536-76-1]
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ncgc00351170.html
Purity
99.05
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=[N+]([O-])ON=C1C(C2=CC=CC=C2OC)=O)C3=C(OC)C=CC=C3
Molecular Formula
C18H14N2O6
Molecular Weight
354.31
References & Citations
[1]Golla K, et al. Small-Molecule Disruptors of the Interaction between Calcium-and Integrin-Binding Protein 1 and Integrin αIIbβ3 as Novel Antiplatelet Agents[J]. ACS Pharmacology & Translational Science, 2024.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Lsx5607-500gEcoli 500 µg (E. coli)
Recombinant Brucella Suis rpsC Protein (aa 1-236)
Sign In for Pricing
View Details 
GTR15343080 1 Vial
Lentiviral human JADE1 shRNA (UAS) - Lentiviral human JADE1 shRNA (UAS, GFP) (100)
Sign In for Pricing
View Details 
VAng-Wyb2554-500gEcoli 500 µg (E. coli)
Recombinant Neisseria Gonorrhoeae gltX Protein (aa 1-464) (strain ATCC 700825 / FA 1090)
Sign In for Pricing
View Details 