NCGC00351170

NCGC00351170 is an antiplatelet agent that disrupts the calcium and integrin-binding protein 1 (CIB1) -αIIbβ3 interaction. NCGC00351170 inhibits thrombin-induced human platelet aggregation[1].

Product Specifications

CAS Number

[886536-76-1]

UNSPSC

12352005

Target

Factor Xa

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ncgc00351170.html

Purity

99.05

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=[N+]([O-])ON=C1C(C2=CC=CC=C2OC)=O)C3=C(OC)C=CC=C3

Molecular Formula

C18H14N2O6

Molecular Weight

354.31

References & Citations

[1]Golla K, et al. Small-Molecule Disruptors of the Interaction between Calcium-and Integrin-Binding Protein 1 and Integrin αIIbβ3 as Novel Antiplatelet Agents[J]. ACS Pharmacology & Translational Science, 2024.