D-Erythro-dihydrosphingosine-d7
D-Erythro-dihydrosphingosine-d7 is the deuterium labeled D-Erythro-dihydrosphingosine. D-Erythro-dihydrosphingosin directly inhibits cytosolic phospholipase A2α (cPLA2α) activity.
Product Specifications
CAS Number
1246304-35-7
Product Name Alternative
Sphinganine (d18:0) -d7
UNSPSC
12352211
Target
Endogenous Metabolite; Isotope-Labeled Compounds; Phospholipase
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Purity
99.00
Solubility
DMF : 10 mg/mL (ultrasonic; warming)
Smiles
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CCCCCCCCCCCC[C@@H](O)[C@@H](N)CO
Molecular Formula
C18H32D7NO2
Molecular Weight
308.55
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Nakamura H, et al. Inhibition of arachidonic acid release and cytosolic phospholipase A2 alpha activity by D-erythro-sphingosine. Eur J Pharmacol. 2004 Jan 19;484 (1) :9-17.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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