BPR1M97

BPR1M97 is a dual-acting mu opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with Ki values of 1.8 and 4.2 nM, respectively. BPR1M97 shows high potency and blood-brain barrier penetration, and produces potent antinociceptive effects[1].

Product Specifications

CAS Number

[2059904-66-2]

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bpr1m97.html

Purity

99.42

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(NCC1N(C)CCC2=C1C=CC=C2)C3=CC=C(Cl)C(Cl)=C3

Molecular Formula

C18H18Cl2N2O

Molecular Weight

349.25

References & Citations

[1]Chao PK, et al. BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, producespotent antinociceptive effects with safer properties than morphine. Neuropharmacology. 2019 Jul 3:107678.