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SR-4995

SR-4995 (CID 16016685) is a highly effective and selective ligand for α-β-hydrolase domain-containing 5 (ABHD5), facilitating the activation of adipose triglyceride lipase (ATGL) by displacing ABHD5 from its inhibitory regulators, perilipin-1 (PLIN1) and PLIN5. It directly interacts with ABHD5, inhibiting its association with PLIN1, and promotes lipolysis in adipocytes and muscle tissues while circumventing PKA-dependent signaling pathways.

Product Specifications

CAS Number

891509-95-8

Product Name Alternative

CID 16016685

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sr-4995.html

Purity

98.26

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1N(C)C2=C(C=CC(NC(NCCCC)=O)=C2)SC3=CC=CC=C31

Molecular Formula

C19H21N3O2S

Molecular Weight

355.45

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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