SR-4995
SR-4995 (CID 16016685) is a highly effective and selective ligand for α-β-hydrolase domain-containing 5 (ABHD5), facilitating the activation of adipose triglyceride lipase (ATGL) by displacing ABHD5 from its inhibitory regulators, perilipin-1 (PLIN1) and PLIN5. It directly interacts with ABHD5, inhibiting its association with PLIN1, and promotes lipolysis in adipocytes and muscle tissues while circumventing PKA-dependent signaling pathways.
Product Specifications
CAS Number
[891509-95-8]
Product Name Alternative
CID 16016685
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sr-4995.html
Purity
98.26
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C)C2=C(C=CC(NC(NCCCC)=O)=C2)SC3=CC=CC=C31
Molecular Formula
C19H21N3O2S
Molecular Weight
355.45
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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