Boc-MLF (TFA)
Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations[1].
Product Specifications
Product Name Alternative
Boc-Met-Leu-Phe-OH (TFA)
UNSPSC
12352005
Target
Formyl Peptide Receptor (FPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Boc-MLF_TFA.html
Purity
99.69
Solubility
DMSO : 150 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC(OC(C)(C)C)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C27H40F3N3O8S
Molecular Weight
623.68
References & Citations
[1]Stenfeldt AL, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30 (6) :224-9. Epub 2007 Aug 9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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