Boc-MLF (TFA)

Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations[1].

Product Specifications

Product Name Alternative

Boc-Met-Leu-Phe-OH (TFA)

UNSPSC

12352005

Target

Formyl Peptide Receptor (FPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Boc-MLF_TFA.html

Purity

99.69

Solubility

DMSO : 150 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC(OC(C)(C)C)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C27H40F3N3O8S

Molecular Weight

623.68

References & Citations

[1]Stenfeldt AL, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30 (6) :224-9. Epub 2007 Aug 9.