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TS-011

TS-011 is a selective inhibitor of 20-Hydroxyeicosatetraenoic acid synthesis.

Product Specifications

CAS Number

339071-18-0

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cytochrome P450; Orphan Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ts-011.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC(C=C(/N=C/NO)C=C1)=C1N2CCOCC2

Molecular Formula

C11H14ClN3O2

Molecular Weight

255.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Marumo T, et al. The inhibitor of 20-HETE synthesis, TS-011, improves cerebral microcirculatory autoregulation impaired by middle cerebral artery occlusion in mice. Br J Pharmacol. 2010 Nov;161 (6) :1391-402.|[2]Hacein-Bey L, et al. Reversal of delayed vasospasm by TS-011 in the dual hemorrhage dog model of subarachnoid hemorrhage. AJNR Am J Neuroradiol. 2006 Jun-Jul;27 (6) :1350-4.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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