Pericosine A
Pericosine A ((+) -Pericosine A) is a topoisomerase II (Topoisomerase II) inhibitor that can be isolated from the Periconia byssoides strain. Pericosine A has significant antitumor activity in vitro and in vivo and can be used in cancer research. Pericosine A also inhibits the protein kinase epidermal growth factor receptor[1].
Product Specifications
CAS Number
200335-68-8
Product Name Alternative
(+) -Pericosine A
UNSPSC
12352211
Target
Topoisomerase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pericosine-a.html
Solubility
10 mM in DMSO
Smiles
COC(C1=C[C@H](O)[C@H](O)[C@H](O)[C@H]1Cl)=O
Molecular Formula
C8H11ClO5
Molecular Weight
222.62
References & Citations
[1]Yamada T, et al. Pericosines, antitumour metabolites from the sea hare-derived fungus Periconia byssoides. Structures and biological activities. Org Biomol Chem. 2007 Dec 21;5 (24) :3979-86.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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