BRL-37344

BRL-37344 (Fosigotifator (THAM sodium) ) is a specific β3-adrenergic receptor agonist. BRL-37344 treatment significantly lowers the body weight of obese mice[1].

Product Specifications

CAS Number

[90730-96-4]

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/brl-37344.html

Purity

99.45

Solubility

0.5 M NaOH : ≥ 100 mg/mL

Smiles

O=C(O)COC1=CC=C(C[C@@H](NC[C@H](C2=CC=CC(Cl)=C2)O)C)C=C1

Molecular Formula

C19H22ClNO4

Molecular Weight

363.84

References & Citations

[1]Wu C, et al. Activating brown adipose tissue for weight loss and lowering of blood glucose levels: a microPET study using obese and diabetic model mice. PLoS One. 2014 Dec 2;9 (12) :e113742.