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EIF5A/eIF5A2 rabbit pAb

Product Specifications

Synonyms

Eukaryotic translation initiation factor 5A-1 (eIF-5A-1;eIF-5A1;Eukaryotic initiation factor 5A isoform 1;eIF-5A;Rev-binding factor;eIF-4D)

Gene ID

1984

UniProt

P63241/Q9GZV4

Cellular Locus

Cytoplasm. Nucleus. Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side. Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions (PubMed:19379712, PubMed:27306458). Nuclear export of hypusinated protein is mediated by XPO4 (PubMed:10944119, PubMed:27306458)..

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human eIF5A/eIF5A2

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000, ELISA (peptide) 1:5000-20000

Molecular Weight

17kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES16765-1.pdf

Observed Molecular Weight

17 kD

Subcellular Location

Cytoplasm . Nucleus . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions (PubMed:19379712, PubMed:27306458) . Nuclear export of hypusinated protein is mediated by XPO4 (PubMed:10944119, PubMed:27306458) . .

Other Product Names

Eukaryotic translation initiation factor 5A-1 (eIF-5A-1; eIF-5A1; Eukaryotic initiation factor 5A isoform 1; eIF-5A; Rev-binding factor; eIF-4D)

Gene ID (Human)

1984

SwissProt (Human)

P63241/Q9GZV4

Available Sizes

Curated Selection

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