3-Phenoxybenzoic acid

3-Phenoxybenzoic acid is the metabolite of pyrethroid insecticides. 3-Phenoxybenzoic acid induces immunotoxicity and oxidative stress, and inhibits the phagocytic ability of macrophages[1].

Product Specifications

CAS Number

[3739-38-6]

Product Name Alternative

3-PBA

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Drug Metabolite; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3-phenoxybenzoic-acid.html

Purity

99.81

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(O)C1=CC=CC(OC2=CC=CC=C2)=C1

Molecular Formula

C13H10O3

Molecular Weight

214.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang X, et al., β-Cypermethrin and its metabolite 3-phenoxybenzoic acid exhibit immunotoxicity in murine macrophages. Acta Biochim Biophys Sin (Shanghai) . 2017 Dec 1;49 (12) :1083-1091.