4-Allylcatechol

4-Allylcatechol (4-Allylpyrocatechol) is a xylan which has oral activity and can be isolated from the root of Piper taiwanense. 4-Allylcatechol has a strong inhibitory activity against collagen-induced platelet aggregation (IC50 = 5.3 μM) . In addition, 4-Allylcatechol has anti-tuberculosis activity against Mycobacterium tuberculosis H37Rv (MIC = 27.6 μg/mL) [1].

Product Specifications

CAS Number

[1126-61-0]

Product Name Alternative

Hydroxychavicol; 4-Allylpyrocatechol

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Antibiotic; Bacterial; Interleukin Related; TNF Receptor

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation

Field of Research

Cancer; Infection; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/4-Allylcatechol.html

Purity

98.60

Solubility

DMSO : ≥ 100 mg/mL

Smiles

OC1=CC=C(CC=C)C=C1O

Molecular Formula

C9H10O2

Molecular Weight

150.17

Precautions

H315, H319

References & Citations

[1]Chen S, et al. Neolignans and phenylpropanoids from the roots of Piper taiwanense and their antiplatelet and antitubercular activities[J]. Phytochemistry, 2013, 93: 203-209.|[2]Ng PL, et al. Piper betle leaf extract enhances the cytotoxicity effect of 5-fluorouracil in inhibiting the growth of HT29 and HCT116 colon cancer cells. J Zhejiang Univ Sci B. 2014 Aug;15 (8) :692-700.|[3]Annavarapu T, et al. Anti-inflammatory and antioxidant activities of 4-allylpyrocatechol and its derivatives with molecular docking and ADMET investigations[J]. Bulletin of the karaganda university chemistry series, 2022, 1 (105) : 50-59.|[4]Pandey A, et al. Hydroxychavicol inhibits immune responses to mitigate cognitive dysfunction in rats. J Neuroimmunol. 2010 Sep 14;226 (1-2) :48-58.