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7-Deoxy-trans-dihydronarciclasine

7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM) . 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice[1][2][3].

Product Specifications

CAS Number

145987-74-2

UNSPSC

12352005

Target

Amyloid-β; TMV

Type

Natural Products

Related Pathways

Anti-infection; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Infection; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/7-deoxy-trans-dihydronarciclasine.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=CC(OCO3)=C3C=C2[C@]4([H])[C@@]([C@@H]([C@@H]([C@H](C4)O)O)O)([H])N1

Molecular Formula

C14H15NO6

Molecular Weight

293.27

References & Citations

[1]Wang YH, et al. Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase. J Nat Prod. 2007 Sep;70 (9) :1458-61.|[2]Zhao D, et al. 7-Deoxy-trans-dihydronarciclasine Isolated from Lycoris chejuensis Inhibits Neuroinflammation in Experimental Models. J Agric Food Chem. 2019 Sep 4;67 (35) :9796-9804.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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