7-Deoxy-trans-dihydronarciclasine
7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM) . 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice[1][2][3].
Product Specifications
CAS Number
145987-74-2
UNSPSC
12352005
Target
Amyloid-β; TMV
Type
Natural Products
Related Pathways
Anti-infection; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/7-deoxy-trans-dihydronarciclasine.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC(OCO3)=C3C=C2[C@]4([H])[C@@]([C@@H]([C@@H]([C@H](C4)O)O)O)([H])N1
Molecular Formula
C14H15NO6
Molecular Weight
293.27
References & Citations
[1]Wang YH, et al. Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase. J Nat Prod. 2007 Sep;70 (9) :1458-61.|[2]Zhao D, et al. 7-Deoxy-trans-dihydronarciclasine Isolated from Lycoris chejuensis Inhibits Neuroinflammation in Experimental Models. J Agric Food Chem. 2019 Sep 4;67 (35) :9796-9804.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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