Mouse IL-22 R alpha 1 Protein, His Tag (MALS & SPR verified)
Interleukin-22 receptor subunit alpha-1 (IL22RA1) is a component of the receptor for IL20, IL22 and IL24.Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Product Specifications
Expression Region
His 16 - Ala 228
Reactivity
Mouse
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Immunology & Inflammation; Metabolism Research
Purity
90%
Form
Powder
Molecular Weight
26.2 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.2 kDa. The protein migrates as 33-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
Q80XZ4
Preservative
PBS, pH 7.4
Available Sizes
Frequently Asked Questions
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