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Canine Sortilin Protein, His Tag

Sortilin is a multifunctional type-I transmembrane protein belonging to the Vps10p-domain receptor family (Vps10p-Domain Receptors, Vps10p-DRs) . Sortilin plays a central role in cellular protein sorting, signal transduction, and metabolism. Its dysfunction is closely related to neurodegenerative diseases, metabolic syndrome, and cancer, and it is a potential therapeutic target for diseases.

Product Specifications

Expression Region

Ser 133 - Asn 810

Reactivity

Canine

Conjugation

Unconjugated

Tag

C-10xHis

Purity

90%

Form

Powder

Molecular Weight

77.6 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 77.6 kDa. The protein migrates as 85-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

A0A8I3RR29

Preservative

PBS, pH 7.4

Available Sizes

Frequently Asked Questions

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