Amilo-5MER

Amilo-5MER (5-MP) is an orally active and selective inhibitor of serum amyloid A (SAA) . It specifically suppresses the release of pro-inflammatory cytokines IL-6 and IL-1β in SAA-activated cells. Amilo-5MER reduces chronic inflammation and alleviates symptoms of diseases such as rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and multiple sclerosis (MS) . It holds potential for research in autoimmune and chronic inflammatory diseases.