Zerumbone

Zerumbone is an orally active natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet. Zerumbone has anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity[1][2][3][4].

Product Specifications

CAS Number

[471-05-6]

UNSPSC

12352211

Hazard Statement

H317, H410

Target

Apoptosis; Bacterial; Caspase; EBV

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-anti-virus

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/zerumbone.html

Purity

99.74

Solubility

DMSO : ≥ 125 mg/mL

Smiles

C/C1=C\CC/C(C)=C/CC(C)(C)/C=C/C1=O

Molecular Formula

C15H22O

Molecular Weight

218.33

Precautions

H317, H410

References & Citations

[1]Abdel Wahab S I, et al. In vitro ultramorphological assessment of apoptosis induced by zerumbone on (HeLa) [J]. BioMed Research International, 2009, 2009.|[2]Sulaiman M R, et al. Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice [J]. Fitoterapia, 2010, 81 (7) : 855-858.|[3]Kim M, et al. Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice [J]. International journal of cancer, 2009, 124 (2) : 264-271.|[4]Kumar S C S, et al. Antibacterial and antimutagenic activities of novel zerumbone analogues [J]. Food Chemistry, 2013, 141 (2) : 1097-1103.