AMPK-IN-4
Product Specifications
UNSPSC Description
AMPK-IN-4 (compound 19) is a potent inhibitor of (AMPK(α1) and AMPK(α2) with IC50s of 393 nM and 141 nM, respectively. AMPK-IN-4 plays an important role in cancer research[1].
Target Antigen
AMPK
Type
Reference compound
Related Pathways
Epigenetics;PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ampk-in-4.html
Solubility
DMSO : 20 mg/mL (ultrasonic;adjust pH to 3 with 1 M HCL)
Smiles
O=C(/C(C1=C2)=C\C3=C(C(C(NCCN)=O)=C(N3)C)C)NC1=CC=C2F
Molecular Weight
342.37
References & Citations
[1]Christopher J Matheson, et al. Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors. Eur J Med Chem. 2020 Jul 1:197:112316.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155943/AMPK-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155943/AMPK-IN-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
873077-70-4
Available Sizes
Curated Selection
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