CYPMPO
CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor activity[1].
Product Specifications
CAS Number
934182-09-9
UNSPSC
12352005
Hazard Statement
H315, H319, H335, H402
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cypmpo.html
Purity
99.00
Solubility
DMSO : 20 mg/mL (ultrasonic; warming)
Smiles
CC1(P2(OCC(C)(C)CO2)=O)[N+]([O-])=CCC1
Molecular Formula
C10H18NO4P
Molecular Weight
247.23
Precautions
H315, H319, H335, H402
References & Citations
[1]Masato Kamibayashi, et al. Synthesis and characterization of a practically better DEPMPO-type spin trap, 5- (2,2-dimethyl-1,3-propoxy cyclophosphoryl) -5-methyl-1-pyrroline N-oxide (CYPMPO) . Free Radic Res. 2006 Nov;40 (11) :1166-72. |[2]Ryohei Umeda, et al. Direct free radical scavenging effects of water-soluble HMG-CoA reductase inhibitors. J Clin Biochem Nutr. 2019 Jan;64 (1) :20-26. |[3]Matsuzaki S, et al. Identification of mitochondrial electron transport chain-mediated NADH radical formation by EPR spin-trapping techniques. Biochemistry 2011, 50, 50, 10792-10803.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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