Andrographolide
Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.
Product Specifications
CAS Number
5508-58-7
Product Name Alternative
Andrographis
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Influenza Virus; NF-κB; Parasite; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection; Autophagy; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/andrographolide.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O=C1OC[C@@H](O)/C1=C\C[C@@H]2C(CC[C@]3([H])[C@](C)(CO)[C@H](O)CC[C@@]23C)=C
Molecular Formula
C20H30O5
Molecular Weight
350.45
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
NF-κB1/p50
Available Sizes
Frequently Asked Questions
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