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BAY 2666605

Product Specifications

UNSPSC Description

BAY 2666605 is an orally active PDE3A and PDE3B inhibitor with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 is a PDE3A-SLFN12 complex inducer (WO2019025562A1; example 135)[1].

Target Antigen

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bay-2666605.html

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

FC(F)(C1=C(C2=CC=C(C=C2)F)C=CC(C([C@@H](O3)C)=NNC3=O)=C1)F

Molecular Weight

352.28

References & Citations

[1]Manuel ELLERMANN, et al. Dihydrooxadiazinones. WO2019025562A1.

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-145924/BAY-2666605-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-145924/BAY-2666605-SDS-MedChemExpress.pdf

Clinical Information

Phase 1

CAS Number

2275774-60-0

Available Sizes

Curated Selection

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