BAY 2666605

BAY 2666605 is an orally active PDE3A and PDE3B inhibitor with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 is a PDE3A-SLFN12 complex inducer (WO2019025562A1; example 135) [1].

Product Specifications

CAS Number

[2275774-60-0]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bay-2666605.html

Purity

99.74

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

FC(F)(C1=C(C2=CC=C(C=C2)F)C=CC(C([C@@H](O3)C)=NNC3=O)=C1)F

Molecular Formula

C17H12F4N2O2

Molecular Weight

352.28

References & Citations

[1]Manuel ELLERMANN, et al. Dihydrooxadiazinones. WO2019025562A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

PDE3

Available Sizes

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