BAY 2666605
BAY 2666605 is an orally active PDE3A and PDE3B inhibitor with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 is a PDE3A-SLFN12 complex inducer (WO2019025562A1; example 135) [1].
Product Specifications
CAS Number
[2275774-60-0]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bay-2666605.html
Purity
99.74
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
FC(F)(C1=C(C2=CC=C(C=C2)F)C=CC(C([C@@H](O3)C)=NNC3=O)=C1)F
Molecular Formula
C17H12F4N2O2
Molecular Weight
352.28
References & Citations
[1]Manuel ELLERMANN, et al. Dihydrooxadiazinones. WO2019025562A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
PDE3
Available Sizes
Curated Selection
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