Boc-GRR-AMC (TFA)
Boc-GRR-AMC (TFA) is a tri-peptide Substrate. Boc-GRR-AMC can be used for a fluorogenic West Nile virus (WNV) substrate, profiling the substrate specificity for the NS2B-NS3 proteases or determining the pH optimum of LdMC activity[1][2].
Product Specifications
UNSPSC
12352209
Target
Virus Protease
Type
Peptides
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/boc-grr-amc-tfa.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC(CNC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C29H44N10O7.xC2HF3O2
Molecular Weight
644.72 (free base)
References & Citations
[1]Nancy Lee, et al. Characterization of metacaspases with trypsin-like activity and their putative role in programmed cell death in the protozoan parasite Leishmania. Eukaryot Cell. 2007 Oct;6 (10) :1745-57.|[2]Manolya Ezgimen, et al.Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease. Antiviral Res. 2012 Apr;94 (1) :18-24.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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