17a-Hydroxypregnenolone

17a-Hydroxypregnenolone is an intermediate in the synthesis of steroid hormones and may be related to the synthesis of sex hormones or adrenal hormones. The sulfate form of 17a-Hydroxypregnenolone (17α-hydroxypregnenolone sulfate) is the main interfering substance in neonatal plasma, which can significantly affect the immunoassay results of 17α-hydroxyprogesterone (17-OHP) by cross-reacting with antibodies[1].

Product Specifications

CAS Number

[387-79-1]

Product Name Alternative

CP 526555 hydrochloride

UNSPSC

12352211

Hazard Statement

H225, H301+H311+H331, H370

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/17a-Hydroxypregnenolone.html

Concentration

10mM

Purity

99.61

Solubility

DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC([C@@]1(O)CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O

Molecular Formula

C21H32O3

Molecular Weight

332.48

Precautions

H225, H301+H311+H331, H370

References & Citations

[1]Wong T, et al. Identification of the steroids in neonatal plasma that interfere with 17 alpha-hydroxyprogesterone radioimmunoassays. Clin Chem. 1992 Sep;38 (9) :1830-7.