Caged MK801

Caged MK801 (cMK801) is a selective, non-competitive, irreversible NMDA receptor open-channel blocker. NVOC cages are neuro pharmocologically compatible[1].

Product Specifications

CAS Number

[217176-91-5]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/caged-mk801.html

Smiles

COC(C=C1COC(N2[C@@H]3CC4=C([C@]2(C)C5=CC=CC=C53)C=CC=C4)=O)=C(C=C1[N+]([O-])=O)OC

Molecular Formula

C26H24N2O6

Molecular Weight

460.48

References & Citations

[1]Antonio Rodríguez-Moreno, et al. Presynaptic induction and expression of timing-dependent long-term depression demonstrated by compartment-specific photorelease of a use-dependent NMDA receptor antagonist. J Neurosci. 2011 Jun 8;31 (23) :8564-8569.