Caged MK801
Caged MK801 (cMK801) is a selective, non-competitive, irreversible NMDA receptor open-channel blocker. NVOC cages are neuro pharmocologically compatible[1].
Product Specifications
CAS Number
[217176-91-5]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/caged-mk801.html
Smiles
COC(C=C1COC(N2[C@@H]3CC4=C([C@]2(C)C5=CC=CC=C53)C=CC=C4)=O)=C(C=C1[N+]([O-])=O)OC
Molecular Formula
C26H24N2O6
Molecular Weight
460.48
References & Citations
[1]Antonio Rodríguez-Moreno, et al. Presynaptic induction and expression of timing-dependent long-term depression demonstrated by compartment-specific photorelease of a use-dependent NMDA receptor antagonist. J Neurosci. 2011 Jun 8;31 (23) :8564-8569.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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