Mouse ALK-7 Protein, His Tag (HPLC verified)
ALK-7, also known as ACVR1C , is a Type I receptor for the TGF-beta family of signaling molecules. Upon ligand binding, it initiates intracellular signaling by phosphorylating cytoplasmic SMAD transcription factors. These activated SMADs then translocate to the nucleus to regulate gene expression, either directly or in complex with other transcription factors.
Product Specifications
Expression Region
Leu 26 - Glu 113
Reactivity
Mouse
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Cell Biology
Purity
90%
Form
Powder
Molecular Weight
11.4 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.4 kDa. The protein migrates as 8-33 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
Q8K348
Preservative
20 mM Tris, 150 mM NaCl, pH 7.5
Available Sizes
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