Human DLL3 Protein, Llama IgG2b Fc Tag, low endotoxin
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.
Product Specifications
Expression Region
Ala 27 - Leu 492
Reactivity
Human
Conjugation
Unconjugated
Tag
N-LlamaFc (LlamaIgG2b)
Field of Research
Stem Cell & Developmental Biology
Endotoxin
0.01 EU per μg
Purity
90%
Form
Powder
Molecular Weight
76.8 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a llama IgG2b Fc tag at the N-terminus. The protein has a calculated MW of 76.8 kDa. The protein migrates as 55-65 kDa and 70-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
Q9NYJ7
Preservative
50 mM Tris, 100 mM Glycine, 225 mM Arginine, 150 mM NaCl, pH 7.5
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