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Mouse IL-5 R alpha / CD125 Protein, His Tag (MALS & SPR verified)

Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125, which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.

Product Specifications

Expression Region

Asp 18 - His 339

Reactivity

Mouse

Conjugation

Unconjugated

Tag

C-10xHis

Field of Research

Immunology & Inflammation; Metabolism Research

Purity

90%

Form

Powder

Molecular Weight

38.7 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.7 kDa. The protein migrates as 50-58 kDa and 75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

P21183

Preservative

PBS, pH 7.4

Available Sizes

Frequently Asked Questions

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