Mouse IL-5 R alpha / CD125 Protein, His Tag (MALS & SPR verified)
Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125, which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.
Product Specifications
Expression Region
Asp 18 - His 339
Reactivity
Mouse
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Immunology & Inflammation; Metabolism Research
Purity
90%
Form
Powder
Molecular Weight
38.7 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
NCBI Accession Number
P21183
Preservative
PBS, pH 7.4
Available Sizes
Frequently Asked Questions
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