Rat CA125 Protein, His Tag (MALS verified)
The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.
Product Specifications
Expression Region
Asn 8776 - Pro 9448
Reactivity
Rat
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Cancer Biology; Immunology & Inflammation
Purity
90%
Form
Powder
Molecular Weight
77.2 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 77.2 kDa. The protein migrates as 33-45 kDa and 90-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
XP_063122364.1
Preservative
PBS, pH 7.4
Available Sizes
Frequently Asked Questions
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