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Human CD109 / CPAMD7 protein, Fc Tag

CD109 is a glycosyl phosphatidylinositol (GPI) -linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. CD109 is expressed in many malignant tumors, including various squamous cell carcinomas and adenocarcinomas, and plays a role as a multifunctional coreceptor.CD109 reportedly associates with transforming growth factor (TGF) -β receptors and negatively regulates TGF-β signaling in keratinocytes. Additionally, CD109 is potentially related to signal transducer and activator of transcription-3 signaling and aberrant cell proliferation.

Product Specifications

UniProt

Q6YHK3

Expression Region

Val 22 - Ser 1269

Reactivity

Human

Conjugation

Unconjugated

Tag

C-Fc

Field of Research

Immunology & Inflammation

Endotoxin

1.0 EU per μg

Purity

90%

Form

Powder

Molecular Weight

166.2 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 166.2 kDa. The protein migrates as >180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

Q6YHK3

Preservative

50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

Available Sizes

Frequently Asked Questions

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