Human IFN-alpha / beta R1 (228-436) Protein, His Tag, low Endotoxin (MALS verified)
Interferon alpha/beta receptor 1 (IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
Product Specifications
UniProt
P17181
Expression Region
Glu 228 - Lys 436
Reactivity
Human
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Infectious Disease & Virology; Immunology & Inflammation
Endotoxin
0.01 EU per μg
Purity
90%
Form
Powder
Molecular Weight
26.1 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.1 kDa. The protein migrates as 35-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
P17181
Preservative
PBS, pH 7.4
Available Sizes
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